CASP14 Chemi-Luminescent ELISA Kit
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96 Wells
£1016,00
OKCD03353-96WELLS
Über dieses Produkt
- SKU:
- OKCD03353
- Zusätzliche Namen:
- apoptosis-related cysteine protease;ARCI12;CASP-14;caspase 14; apoptosis-related cysteine peptidase;caspase 14; apoptosis-related cysteine protease;caspase-14.
- Weitere Details:
- Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum (PubMed:15556625). Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin (By similarity). In vitro has a preference for the substrate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF (PubMed:16854378; PubMed:19960512). Involved in processing of prosaposin in the epidermis (By similarity). May be involved in retinal pigment epithelium cell barrier function (PubMed:25121097). Involved in DNA degradation in differentiated keratinocytes probably by cleaving DFFA/ICAD leading to liberation of DFFB/CAD (PubMed:24743736).
- Gendetails:
- caspase 14
- Proteindetails:
- Caspase-14
- Empfindlichkeit:
- 0.312 ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php