EPAS1 ELISA Kit
Produktgrößen
96 Wells
£929,00
OKCD02540-96WELLS
Über dieses Produkt
- SKU:
- OKCD02540
- Zusätzliche Namen:
- endothelial PAS domain-containing protein 1;EPAS-1;HIF2 alpha;HIF-2 alpha;Hif2a;HIF2-alpha;HIF-2-alpha;HLF;hypoxia inducible factor 2; alpha subunit;hypoxia inducible factor 2a;hypoxia-inducible factor 2-alpha.
- Weitere Details:
- Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (By similarity). Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD (By similarity).
- Gendetails:
- endothelial PAS domain protein 1
- Proteindetails:
- Endothelial PAS domain-containing protein 1
- Empfindlichkeit:
- 27 pg/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php