CAV1 ELISA Kit
Produktgrößen
96 Wells
£814,00
OKCD02426-96WELLS
Über dieses Produkt
- SKU:
- OKCD02426
- Zusätzliche Namen:
- Cav;Cav-1;cave;caveolin; caveolae protein 1;caveolin; caveolae protein; 22 kDa;caveolin-1.
- Weitere Details:
- Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation (By similarity). Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (PubMed:10816572). Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (By similarity). Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (PubMed:19546242).
- Gendetails:
- caveolin 1; caveolae protein
- Proteindetails:
- Caveolin-1
- Empfindlichkeit:
- 6.7 pg/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php