CC2D1A ELISA Kit
Produktgrößen
96 Wells
£955,00
OKCD02041-96WELLS
Über dieses Produkt
- SKU:
- OKCD02041
- Zusätzliche Namen:
- Aki-1;Akt kinase-interacting protein 1;coiled-coil and C2 domain-containing protein 1A;five prime repressor element under dual repression-binding protein 1;five repressor element under dual repression-binding protein 1;FRE under dual repression-binding protein 1;FREUD-1;Freud-1/Aki1;Lgd2;MRT3;putative NF-kappa-B-activating protein 023N;putative NFkB activating protein;TAPE;TBK1-associated protein in endolysosomes.
- Weitere Details:
- Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses (By similarity). Plays distinct roles depending on its localization. When cytoplasmic; acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome; regulates spindle pole localization of the cohesin subunit SCC1/RAD21; thereby mediating centriole cohesion during mitosis.
- Gendetails:
- coiled-coil and C2 domain containing 1A
- Proteindetails:
- Coiled-coil and C2 domain-containing protein 1A
- Empfindlichkeit:
- < 0.128 ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php