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Assay-Kits & ELISAs

ASAH2 ELISA Kit

Produktgrößen
96 Wells
£868,00
OKCD01831-96WELLS
Über dieses Produkt
SKU:
OKCD01831
Zusätzliche Namen:
acylsphingosine deacylase 2;BCDase;HNAC1;LCDase;mitochondrial ceramidase;N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2;N-acylsphingosine amidohydrolase 2;NCDase;N-CDase;neutral ceramidase;neutral/alkaline ceramidase;non-lysosomal ceramidase.
Weitere Details:
Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5 (PubMed:10781606; PubMed:26190575). Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide; thereby preventing ceramide-induced apoptosis; and generating sphingosine; a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.
Gendetails:
N-acylsphingosine amidohydrolase 2
Proteindetails:
Neutral ceramidase
Empfindlichkeit:
< 0.31 ng/mL
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Assay Kits: ELISAs