ADRBK1 ELISA Kit
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96 Wells
£868,00
OKCD01648-96WELLS
Über dieses Produkt
- SKU:
- OKCD01648
- Zusätzliche Namen:
- ADRBK1;adrenergic beta receptor kinase 1;BARK1;beta-adrenergic receptor kinase 1;beta-ARK-1;BETA-ARK1;G-protein coupled receptor kinase 2.
- Weitere Details:
- Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors; probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner (PubMed:19306925; PubMed:19715378). Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by faciltating the trafficking of SMO into the cilium and the stimulation of SMO activity (By similarity).
- Gendetails:
- G protein-coupled receptor kinase 2
- Proteindetails:
- Beta-adrenergic receptor kinase 1
- Empfindlichkeit:
- < 0.125 ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php