Adam10 High Sensitivity ELISA Kit
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96 Wells
£868,00
OKCD01334-96WELLS
Über dieses Produkt
- SKU:
- OKCD01334
- Zusätzliche Namen:
- 1700031C13Rik;a disintegrin and metalloprotease domain (ADAM) 10;disintegrin and metalloproteinase domain-containing protein 10;kuz;kuzb;kuzbanian;kuzbanian protein homolog;MADM;mammalian disintegrin-metalloprotease.
- Weitere Details:
- Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface (By similarity). Responsible for the proteolytic release of several other cell-surface proteins; including heparin-binding epidermal growth-like factor; ephrin-A2; CD44; CDH2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP) at '687-Lys-|-Leu-688' (By similarity). Contributes to the normal cleavage of the cellular prion protein (By similarity). Involved in the cleavage of the adhesion molecule L1 at the cell surface and in released membrane vesicles; suggesting a vesicle-based protease activity (By similarity). Controls also the proteolytic processing of Notch and mediates lateral inhibition during neurogenesis (PubMed:9244301). Responsible for the FasL ectodomain shedding and for the generation of the remnant ADAM10-processed FasL (FasL APL) transmembrane form (By similarity). Also cleaves the ectodomain of the integral membrane proteins CORIN and ITM2B (By similarity). May regulate the EFNA5-EPHA3 signaling (By similarity).
- Gendetails:
- a disintegrin and metallopeptidase domain 10
- Proteindetails:
- Disintegrin and metalloproteinase domain-containing protein 10
- Empfindlichkeit:
- 3.7 pg/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php