ABCA4 ELISA Kit
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96 Wells
£868,00
OKCD00914-96WELLS
Über dieses Produkt
- SKU:
- OKCD00914
- Zusätzliche Namen:
- ABC10;ABCR;ARMD2;ATP binding cassette transporter;ATP-binding cassette sub-family A member 4;ATP-binding cassette transporter; retinal-specific;ATP-binding cassette; sub-family A (ABC1); member 4;ATP-binding transporter; retina-specific;CORD3;FFM;photoreceptor rim protein;retinal-specific ATP-binding cassette transporter;retinal-specific phospholipid-transporting ATPase ABCA4;retina-specific ABC transporter;RIM ABC transporter;RIM protein;RMP;RP19;stargardt disease protein;STGD;STGD1.
- Weitere Details:
- In the visual cycle; acts as an inward-directed retinoid flipase; retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface; ATR is reduced to vitamin A by trans-retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse; removing ATR/NR-PE from the extracellular photoreceptor surfaces during bleach recovery.
- Gendetails:
- ATP binding cassette subfamily A member 4
- Proteindetails:
- Retinal-specific ATP-binding cassette transporter
- Empfindlichkeit:
- < 0.128 ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php