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Assay-Kits & ELISAs

DROSHA ELISA Kit

Produktgrößen
96 Wells
£868,00
OKCD00897-96WELLS
Über dieses Produkt
SKU:
OKCD00897
Zusätzliche Namen:
drosha; double-stranded RNA-specific endoribonuclease;ETOHI2;HSA242976;nuclear RNase III Drosha;p241;Protein Drosha;putative protein p241 which interacts with transcription factor Sp1;putative ribonuclease III;RANSE3L;ribonuclease 3;Ribonuclease III;ribonuclease type III; nuclear;RN3;RNase III;RNASE3L;RNASEN.
Weitere Details:
Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex; DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.
Gendetails:
drosha ribonuclease III
Proteindetails:
Ribonuclease 3
Empfindlichkeit:
< 0.126 ng/mL
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Assay Kits: ELISAs