ABI1 ELISA Kit
Produktgrößen
96 Wells
£868,00
OKCD00577-96WELLS
Über dieses Produkt
- SKU:
- OKCD00577
- Zusätzliche Namen:
- Abelson interactor 1;ABI-1;abl interactor 1;abl-binding protein 4;ABLBP4;Abl-interactor protein 1 long;E3B1;eps8 SH3 domain-binding protein;interactor protein AblBP4;nap1 binding protein;Nap1-binding protein;NAP1BP;spectrin SH3 domain-binding protein 1;SSH3BP;SSH3BP1.
- Weitere Details:
- May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro; a trimeric complex of ABI1; EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodia and there seems to regulate WASF1 protein level. In brain; seems to regulate the dendritic outgrowth and branching as well as to determine the shape and number of synaptic contacts of developing neurons.
- Gendetails:
- abl interactor 1
- Proteindetails:
- Abl interactor 1
- Empfindlichkeit:
- < 0.055 ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php