Cd5l ELISA Kit
Produktgrößen
96 wells/kit; with removable strips.
£788,00
OKBB01546-96WELLS
Über dieses Produkt
- SKU:
- OKBB01546
- Zusätzliche Namen:
- CD5 antigen-like;Apoptosis inhibitor expressed by macrophages ;mAIM ;Apoptosis inhibitory 6;SP-alpha ;Cd5l;Aim; Api6;
- Weitere Details:
- CD5 antigen-like; also known as Sp alpha and AIM; is a protein that in humans is encoded by the CD5L gene. It is mapped to 1q21-q23 by fluorescence in situ hybridization. It is found that Aim expression is induced in mouse macrophages in response to loading with highly oxidized low density lipoprotein (oxLDL); and that Aim is expressed in foam cells within atherosclerotic lesions. Both the expression of Aim in lesions and its induction by oxLDL require Lxr /Rxr heterodimers. Aim-null macrophages are highly susceptible to oxLDL-induced apoptosis in vitro and undergo accelerated apoptosis in atherosclerotic lesions in vivo. Double knockout of Aim and Ldlr reduce atherosclerotic lesions. Therefore; it is concluded that AIM expression protects macrophages from apoptosis within atherosclerotic lesions; promoting early lesion development.
- Gendetails:
- CD5 antigen-like
- Immunogen:
- Expression system for standard: NS0; Immunogen sequence: E22-V352
- Proteindetails:
- CD5 antigen-like
- Empfindlichkeit:
- <10 pg/ml
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs