AKR1C3 ELISA Kit
Produktgrößen
96 wells/kit; with removable strips.
£1096,00
OKBB01282-96WELLS
Über dieses Produkt
- SKU:
- OKBB01282
- Zusätzliche Namen:
- Aldo-keto reductase family 1 member C3 (EC:1.-.-.-); 17-beta-hydroxysteroid dehydrogenase type 5; 17-beta-HSD 5; 3-alpha-HSD type II; brain; 3-alpha-hydroxysteroid dehydrogenase type 2 (EC:1.1.1.357); 3-alpha-HSD type 2; Chlordecone reductase homolog HAKRb; Dihydrodiol dehydrogenase 3; DD-3; DD3; Dihydrodiol dehydrogenase type I; HA1753; Indanol dehydrogenase (EC:1.1.1.112); Prostaglandin F synthase (EC:1.1.1.188); PGFS; Testosterone 17-beta-dehydrogenase 5; Trans-1; 2-dihydrobenzene-1; 2-diol dehydrogenase (EC:1.3.1.20); AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS
- Weitere Details:
- Aldo-keto reductase family 1 member C3 (AKR1C3); also known as 17β-hydroxysteroid dehydrogenase type 5 (17β-HSD5; HSD17B5) is a key steroidogenic enzyme that in humans is encoded by the AKR1C3 gene. It is mapped to 10p15.1. This gene encodes a member of the aldo/keto reductase superfamily; which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2; PGH2 and phenanthrenequinone (PQ); and the oxidation of 9alpha;11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma; and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene.
- Gendetails:
- aldo-keto reductase family 1 member C3
- Immunogen:
- Expression system for standard: E.coli; Immunogen sequence: M1-Y323
- Proteindetails:
- Aldo-keto reductase family 1 member C3
- Empfindlichkeit:
- <10 pg/ml
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs