Bmp10 ELISA Kit
Produktgrößen
96 wells/kit; with removable strips.
£1096,00
OKBB01236-96WELLS
Über dieses Produkt
- SKU:
- OKBB01236
- Zusätzliche Namen:
- Bone morphogenetic protein 10; BMP-10; BMP10
- Weitere Details:
- Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. This gene is mapped to 6; 6 D1. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. BMP-10 plays a crucial role in the development of the embryonic heart by acting to stimulate and maintain cardiomyocyte proliferation. It can signal through various receptor complexes usually containing BMPR-1A; BMPR-1B; ALK1; ALK3; or ALK6. The interaction of BMP-10 with its specific receptors can induce signaling initiated by the phosphorylation of SMAD transcription factors; including SMAD1; SMAD5; or SMAD8; but can also induce SMAD independent processes. BMP-10 is structurally related to BMP-9; and both can inhibit endothelial cell proliferation and migration. Recombinant human BMP-10 is a 24.4 kDa homodimeric disulfide-linked protein consisting of two 108 amino acid subunits; which correspond to amino acid residues 317 to 424 of the full-length BMP-10 precursor.
- Gendetails:
- bone morphogenetic protein 10
- Immunogen:
- Expression system for standard: NS0; Immunogen sequence: N314-R421
- Proteindetails:
- Bone morphogenetic protein 10
- Empfindlichkeit:
- <10 pg/ml
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs