Cxadr ELISA Kit
Produktgrößen
96 wells/kit; with removable strips.
£766,00
OKBB01202-96WELLS
Über dieses Produkt
- SKU:
- OKBB01202
- Zusätzliche Namen:
- Coxsackievirus and adenovirus receptor homolog; CAR; rCAR; Cxadr; Car
- Weitere Details:
- CXADR(Coxsackie virus and adenovirus receptor) is a protein that in humans is encoded by the CXADR gene; also known as CAR;CVB3-binding protein; this gene is mapped to 11q11. Coxsackievirus B-adenovirus receptor. The CAR cDNA encodes a predicted 365-amino acid polypeptide that contains a single transmembrane domain and is a member of the immunoglobulin superfamily. By Northern blot analysis; they detected highest expression of 1.4-kb and 6-kb CXADR transcripts in pancreas; brain; heart; small intestine; testis; and prostate; lower expression in liver and lung; and no expression in kidney; placenta; peripheral blood leukocytes; thymus; and spleen. In comparison; mouse Cxadr showed highest expression in liver; and lower levels in kidney; heart; lung; and brain. The protein encoded by this gene is a type I membrane receptor for group B coxsackie viruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15; 18; and 21. CAR is strongly expressed in the developing central nervous system. It functions as a homophilic and also as a heterophilic cell adhesion molecule through its interactions with extracellular matrix glycoproteins ; such as: fibronectin; agrin; laminin-1 and tenascin-R.
- Gendetails:
- CXADR; Ig-like cell adhesion molecule
- Immunogen:
- Expression system for standard: NS0; Immunogen sequence: L20-G237
- Proteindetails:
- Coxsackievirus and adenovirus receptor homolog
- Empfindlichkeit:
- <10 pg/ml
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs