FCGRT ELISA Kit
Produktgrößen
96 wells/kit; with removable strips.
£1096,00
OKBB01003-96WELLS
Über dieses Produkt
- SKU:
- OKBB01003
- Zusätzliche Namen:
- FCGRT; FcRn alpha chain; FcRn; IgG Gc receptor; Neonatal Fc receptor; Q61559
- Weitere Details:
- The neonatal Fc receptor (FcRn); also known as the Brambell receptor; is a protein that in humans is encoded by the FCGRT gene. The neonatal Fc receptor is an Fc receptor which is similar in structure to the MHC class I molecule and also associates with beta-2-microglobulin. It was first discovered in rodents as a unique receptor capable of transporting IgG from mother's milk across the epithelium of newborn rodent's gut into the newborn's bloodstream. Further studies revealed a similar receptor in humans; leading to the naming as a neonatal Fc receptor. In humans; however; it is found in the placenta to help facilitate transport of mother's IgG to the growing fetus and it has also been shown to play a role in monitoring IgG turnover. Neonatal Fc receptor expression is up-regulated by the proinflammatory cytokine;TNF-α; and down-regulated by IFN-γ.
- Gendetails:
- Fc fragment of IgG receptor and transporter
- Immunogen:
- Expression system for standard: NS0; Immunogen sequence: S22-S297
- Proteindetails:
- IgG receptor FcRn large subunit p51
- Empfindlichkeit:
- <10 pg/ml
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs