GRN ELISA Kit
Produktgrößen
96 wells/kit; with removable strips.
£766,00
OKBB00872-96WELLS
Über dieses Produkt
- SKU:
- OKBB00872
- Zusätzliche Namen:
- Acrogranin; CLN11; GEP; GP88; Granulin A; Granulin B; Granulin C; Granulin D; Granulin E; Granulin epithelin; Granulin F; Granulin G; Granulin-7; Granulins; GRN; GRN_HUMAN; PC cell derived growth factor; PCDGF; PEPI; PGRN; Proepithelin; Progranulin
- Weitere Details:
- Granulin; also known as Proepithelin(PEPI) is a protein that in humans is encoded by the GRN gene. This gene is mapped to 17q21.31. Granulins are a family of secreted; glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein; progranulin; is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active; 6 kDa peptides. These smaller cleavage products are named granulin A; granulin B; granulin C; etc. Epithelins 1 and 2 are synonymous with granulins A and B; respectively. Both the peptides and intact granulin protein regulate cell growth. However; different members of the granulin protein family may act as inhibitors; stimulators; or have dual actions on cell growth. Granulin family members are important in normal development; wound healing; and tumorigenesis.
- Gendetails:
- granulin
- Immunogen:
- Expression system for standard: NS0; Immunogen sequence: T18-L593
- Proteindetails:
- Granulins
- Empfindlichkeit:
- <50 pg/ml
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs