BMP4 ELISA Kit
Produktgrößen
96 wells/kit; with removable strips.
£766,00
OKBB00692-96WELLS
Über dieses Produkt
- SKU:
- OKBB00692
- Zusätzliche Namen:
- BMP 2B; BMP 4; BMP2B; BMP2B1; BOMPR4A; Bone morphogenetic protein 2B; Bone morphogenetic protein 4; DVR4; OTTMUSP00000021065; OTTMUSP00000021066; ZYME
- Weitere Details:
- Bone morphogenetic protein 4 is a protein that in humans is encoded by the BMP4 gene which is located to 14q22-q23. The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. BMP4 is a polypeptide belonging to the TGF-β superfamily of proteins. It; like other bone morphogenetic proteins; is involved in bone and cartilage development; specifically tooth and limb development and fracture repair. It has been shown to be involved in muscle development; bone mineralization; and uteric bud development. BMP4 has also been implicated in Fibrodysplasia Ossificans Progressiva in which it is underexpressed. In human embryonic development; BMP4 is a critical signaling molecule required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. BMP4 is secreted from the dorsal portion of the notochord; and it acts in concert with sonic hedgehog (released from the ventral portion of the notochord) to establish a dorsal-ventral axis for the differentiation of later structures. Also; BMP4 stimulates differentiation of overlying ectodermal tissue. Inhibition of the BMP4 signal (by chordin; noggin; or follistatin) causes the ectoderm to differentiate into the neural plate.
- Gendetails:
- bone morphogenetic protein 4
- Immunogen:
- Expression system for standard: CHO; Immunogen sequence: S293-R408
- Proteindetails:
- Bone morphogenetic protein 4
- Empfindlichkeit:
- <10 pg/ml
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs