CD40L ELISA Kit
Produktgrößen
96 wells/kit; with removable strips.
£766,00
OKBB00633-96WELLS
Über dieses Produkt
- SKU:
- OKBB00633
- Zusätzliche Namen:
- CD154; CD40 antigen ligand; CD40 ligand; CD40-L; CD40L_HUMAN; CD40LG; gp39; HIGM1; IGM; IMD3; soluble form; T B cell activating molecule; T BAM; T cell antigen Gp39; T-cell antigen Gp39; TNF related activation protein; TNF-related activation protein; TNFSF5; TrAP; Tumor necrosis factor (ligand) superfamily member 5; Tumor necrosis factor (ligand) superfamily; member 5 (hyper-IgM syndrome); Tumor necrosis factor ligand superfamily member 5
- Weitere Details:
- CD40 ligand (CD40L) is a type II membrane protein of 261 amino acids on activated T cells that induces B cell proliferation and immunoglobulin secretion. It has homology with tumour necrosis factor-alpha and -beta; and has important functions in B-cell activation and differentiation. Human CD40L with 5 exons; is mapped to the proximal region of the mouse X chromosome on Xq26.3-27.1; and can be detected on T cells but is absent from B cells and monocytes. Since CD40L is expressed on platelets and released from them on activation; its predictive value as a marker for clinical outcome and the therapeutic effect of inhibition of glycoprotein IIb/IIIa receptor in patients with acute coronary syndromes was investigated. The soluble CD40L may be involved in the process of restenosis and that it exerts its effect by triggering a complex group of inflammatory reactions on endothelial and mononuclear cells.CD40L plays a central role in the pathophysiology of acute coronary syndromes; and has a role in the pathogenesis of coronary artery lesions.
- Gendetails:
- CD40 ligand
- Immunogen:
- Expression system for standard: NS0; Immunogen sequence: E61-L260
- Proteindetails:
- CD40 ligand
- Empfindlichkeit:
- <10 pg/ml
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs