DLL4 ELISA Kit
Produktgrößen
96 wells/kit; with removable strips.
£766,00
OKBB00576-96WELLS
Über dieses Produkt
- SKU:
- OKBB00576
- Zusätzliche Namen:
- Delta 4; Delta4; Delta ligand 4; Delta like 4; DLL 4; DLL4; hdelta2; Homeobox protein DLL-4; Notch ligand delta 2; Notch ligand DLL4; XDLL-4; Q9NR61
- Weitere Details:
- Delta like ligand 4 is a protein that in humans is encoded by the DLL4 gene. It is mapped to 15q15.1. This gene is a homolog of the Drosophila delta gene. DLL4 is a transmembrane ligand for Notch receptors that shows restricted expression to endothelial cells (ECs); in particular to arteries and capillaries; and is involved in vascular development; and it also appeared to be a major trigger of Notch receptor activities previously implicated in arterial and vascular development. Mouse DLL4 could activate mouse Notch1 and mouse Notch4. DLL4 acts as a negative regulator of tumor angiogenesis; its blockade results in the striking uncoupling of tumor growth from vessel density; presenting a novel therapeutic approach even for tumors resistant to anti-VEGF therapies. In addition to it; this gene also plays an important role in promoting Th17 effector activity during mycobacterial challenge.
- Gendetails:
- delta-like 4 (Drosophila)
- Immunogen:
- Expression system for standard: NS0; Immunogen sequence: S28-P525
- Proteindetails:
- Delta-like protein 4
- Empfindlichkeit:
- <10 pg/ml
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs