Cystatin B ELISA Kit
Produktgrößen
96 wells/kit; with removable strips.
£766,00
OKBB00539-96WELLS
Über dieses Produkt
- SKU:
- OKBB00539
- Zusätzliche Namen:
- CHROW21; CPI B; CPI-B; CST6; CSTB; Cystatin B; Cystatin-B; CYTB; CYTB_HUMAN; EPM1; EPM1A; Liver thiol proteinase inhibitor; PME; Stefin-B; STFB; ULD
- Weitere Details:
- Cystatin B (CSTB); also called STFB; is a small protein that is a member of the superfamily of cysteine protease inhibitors. It has been isolated from human spleen and liver and its amino acid sequence has been fully determined. The cystatin B gene is located on 21q22.3. It is widely distributed and is localized mostly intracellularly; but has been found extracellularly. The protein is able to form a dimer stabilized by noncovalent forces; inhibiting papain and cathepsins l; h and b. Its role is thought to be as a protector against the proteinases leaking from lysosomes. A cystatin B multiprotein complex might have a specific cerebellar function; and that the loss of this function might contribute to the etiopathogenesis of EPM1. Upon differentiation to myotubes; CSTB becomes excluded from the nucleus and lysosomes; suggesting that the subcellular distribution of CSTB is dependent on the differentiation status of the cell.
- Gendetails:
- cystatin B (stefin B)
- Immunogen:
- Expression system for standard: E.coli; Immunogen sequence: M2-F98
- Proteindetails:
- Cystatin-B
- Empfindlichkeit:
- <10 pg/ml
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs