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Assay-Kits & ELISAs

Cardiotrophin-1 ELISA Kit

Produktgrößen
96 wells/kit; with removable strips.
£766,00
OKBB00279-96WELLS
Über dieses Produkt
SKU:
OKBB00279
Zusätzliche Namen:
Cardiophin 1; Cardiophin1; Cardiotrophin I; Cardiotrophin-1; CardiotrophinI; CT 1; CT-1; CT1; CTF 1; Ctf1; CTF1_HUMAN
Weitere Details:
Cardiotrophin-1 (CT-1) is a member of the family of cytokines that includes leukemia inhibitory factor (LIF); ciliary neurotrophic factor (CNTF); oncostatin M (OSM); interleukin-6 (IL6); and interleukin-11 (IL11). And the CT-1 gene is mapped to 1p21-p13. The human CT-1 protein contains 201 amino acids and shares 80% amino acid identity with the 203-amino acid mouse CT-1 sequence; however; unlike the mouse protein; human CT-1 has 2 rather than 1 cys and has no N-glycosylation site. Despite lacking a signal sequence; secreted CT-1 and mouse CT-1 induce cardiac myocyte hypertrophy in cell culture and bind to both mouse and human LIFR but not to OSMR. Furthermore; A 1.7-kb CT-1 transcript was detected at high levels in heart; skeletal muscle; prostate; and ovary. Low levels were detected in lung; kidney; pancreas; thymus; testis; and small intestine; with little or no expression detected in brain; placenta; spleen; colon; and peripheral blood leukocytes. And it was also observed strong expression in fetal lung and kidney.
Gendetails:
cardiotrophin 1
Immunogen:
Expression system for standard: E.coli; Immunogen sequence: S2-A201
Proteindetails:
Cardiotrophin-1
Empfindlichkeit:
<10 pg/ml
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 4C for 6 months; at -20C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Hersteller:
Aviva Systems Biology
Typ:
Assay Kits: ELISAs