CST3 Antibody
Produktgrößen
100ul
£392,00
OASG07733-100UL
Über dieses Produkt
- SKU:
- OASG07733
- Zusätzliche Namen:
- ARMD11; HEL-S-2
- Klonalität:
- Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors; while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily; including the type 1 cystatins (stefins); type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions; where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases; which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions; establishing its role in vascular disease. In addition; this protein has been shown to have an antimicrobial function; inhibiting the replication of herpes simplex virus. Alternative splicing results in multiple transcript variants encoding a single protein.
- Gendetails:
- cystatin C
- Host:
- Mouse
- Immunogen:
- Recombinant Protein of Cystatin C
- Isotyp:
- IgG1
- Proteindetails:
- Cystatin-C
- Aufreinigung:
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php