ERCC5 Antibody - N-terminal region
Produktgrößen
100ul
£359,00
OASG07592-100UL
Über dieses Produkt
- SKU:
- OASG07592
- Zusätzliche Namen:
- XPG; UVDR; XPGC; COFS3; ERCM2; ERCC5-201
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes; including RNA polymerase II transcription; and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G); which is also referred to as xeroderma pigmentosum VII (XP7); a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome; which is characterized by severe growth defects; mental retardation; and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic; immunoglobulin-like variable motif containing) gene.
- Gendetails:
- excision repair cross-complementation group 5
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the N-terminal region of human XPG. Location: 100-180aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 130 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php