ESPL1 Antibody
Produktgrößen
100ul
£359,00
OASG06575-100UL
Über dieses Produkt
- SKU:
- OASG06575
- Zusätzliche Namen:
- ESP1; SEPA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates; sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1; or separase; which initiates the final separation of sister chromatids (Sun et al.; 2009 [PubMed 19345191]).[supplied by OMIM; Nov 2010]
- Gendetails:
- extra spindle pole bodies like 1; separase
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human Separase around the phosphorylation site of S801. Location: 740-820aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 230 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php