CDK5R1 Antibody - N-terminal region
Produktgrößen
100ul
£359,00
OASG05511-100UL
Über dieses Produkt
- SKU:
- OASG05511
- Zusätzliche Namen:
- p23; p25; p35; CDK5R; NCK5A; CDK5P35; p35nck5a
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.
- Gendetails:
- cyclin-dependent kinase 5; regulatory subunit 1 (p35)
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived between 30-110 aa from the N-terminal region of human p35.
- Isotyp:
- IgG
- Molekulargewicht:
- 35 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20Â[o]C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php