CDKN1B Antibody
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100ul
£359,00
OASG05493-100UL
Über dieses Produkt
- SKU:
- OASG05493
- Zusätzliche Namen:
- KIP1; MEN4; CDKN4; MEN1B; P27KIP1
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a cyclin-dependent kinase inhibitor; which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes; and thus controls the cell cycle progression at G1. The degradation of this protein; which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes; is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).
- Gendetails:
- cyclin-dependent kinase inhibitor 1B (p27; Kip1)
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human p27 around the phosphorylation site of T157. Location: 100-180aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 27 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php