CDKN2C Antibody - C-terminal region
Produktgrößen
100ul
£359,00
OASG05484-100UL
Über dieses Produkt
- SKU:
- OASG05484
- Zusätzliche Namen:
- p18; INK4C; p18-INK4C
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6; and prevent the activation of the CDK kinases; thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis; as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene; which encode an identical protein; have been reported.
- Gendetails:
- cyclin-dependent kinase inhibitor 2C (p18; inhibits CDK4)
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the C-terminal region of human p18. Location: 80-160aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 18 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php