GRAP Antibody - N-terminal region
Produktgrößen
100ul
£359,00
OASG03203-100UL
Über dieses Produkt
- SKU:
- OASG03203
- Zusätzliche Namen:
- DFNB114
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin; and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general; it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.
- Gendetails:
- GRB2-related adaptor protein
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the N-terminal region of human Grap. Location: 10-90aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 28 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php