FFAR4 Antibody - middle region
Produktgrößen
100ul
£359,00
OASG03111-100UL
Über dieses Produkt
- SKU:
- OASG03111
- Zusätzliche Namen:
- GT01; PGR4; BMIQ10; GPR120; GPR129; O3FAR1
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects; particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect; but independent of the G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation.
- Gendetails:
- free fatty acid receptor 4
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human GPR120. Location: 190-270aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 38 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php