GRID2 Antibody - C-terminal region
Produktgrößen
100ul
£359,00
OASG03066-100UL
Über dieses Produkt
- SKU:
- OASG03066
- Zusätzliche Namen:
- GluD2; SCAR18
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog; associated with the phenotype named 'lurcher'; in the heterozygous state leads to ataxia resulting from selective; cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause cerebellar ataxia in humans.
- Gendetails:
- glutamate receptor; ionotropic; delta 2
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the C-terminal region of human GluR-Delta2. Location: 800-880aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 113 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php