GNE Antibody - C-terminal region
Produktgrößen
100ul
£359,00
OASG03045-100UL
Über dieses Produkt
- SKU:
- OASG03045
- Zusätzliche Namen:
- NM; DMRV; IBM2; Uae1; GLCNE
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc); a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes; including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria; autosomal recessive inclusion body myopathy; and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms.
- Gendetails:
- glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the C-terminal region of human GLCNE. Location: 570-650aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 80 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php