CCDC88A Antibody
Produktgrößen
100ul
£359,00
OASG03037-100UL
Über dieses Produkt
- SKU:
- OASG03037
- Zusätzliche Namen:
- APE; GIV; GRDN; PEHO; HkRP1; PEHOL; GIRDIN; KIAA1212
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- Gendetails:
- coiled-coil domain containing 88A
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human Girdin around the phosphorylation site of S1417. Location: 1360-1440aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 216 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php