GHRL Antibody - middle region
Produktgrößen
100ul
£359,00
OASG03029-100UL
Über dieses Produkt
- SKU:
- OASG03029
- Zusätzliche Namen:
- MTLRP
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides; ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty; whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities; including hunger; reward perception via the mesolimbic pathway; gastric acid secretion; gastrointestinal motility; and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake; but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin; including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition; antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.
- Gendetails:
- ghrelin/obestatin prepropeptide
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human Ghrelin.
- Isotyp:
- IgG
- Molekulargewicht:
- 13 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php