GAD1 Antibody - C-terminal region
Produktgrößen
100ul
£359,00
OASG02912-100UL
Über dieses Produkt
- SKU:
- OASG02912
- Zusätzliche Namen:
- GAD; SCP; CPSQ1; DEE89
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes one of several forms of glutamic acid decarboxylase; identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products; the predominant 67-kD form and a less-frequent 25-kD form.
- Gendetails:
- glutamate decarboxylase 1 (brain; 67kDa)
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the C-terminal region of human GAD-65/67. Location: 520-600aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 65 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php