FLT3 Antibody
Produktgrößen
100ul
£359,00
OASG02760-100UL
Über dieses Produkt
- SKU:
- OASG02760
- Zusätzliche Namen:
- FLK2; STK1; CD135; FLK-2
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain; which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis; proliferation; and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
- Gendetails:
- fms-related tyrosine kinase 3
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human Flt3 around the phosphorylation site of Y599. Location: 540-620aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 160 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php