FGFR3 Antibody - middle region
Produktgrößen
100ul
£359,00
OASG02706-100UL
Über dieses Produkt
- SKU:
- OASG02706
- Zusätzliche Namen:
- ACH; CEK2; JTK4; CD333; HSFGFR3EX
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a member of the fibroblast growth factor receptor (FGFR) family; with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region; composed of three immunoglobulin-like domains; a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors; setting in motion a cascade of downstream signals; ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
- Gendetails:
- fibroblast growth factor receptor 3
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human FGFR-3. Location: 100-180aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 95 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php