FANCD2 Antibody
Produktgrößen
100ul
£359,00
OASG02661-100UL
Über dieses Produkt
- SKU:
- OASG02661
- Zusätzliche Namen:
- FA4; FAD; FACD; FAD2; FA-D2; FANCD
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks; both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division; particularly after replication stress. Required for the targeting; or stabilization; of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.
- Gendetails:
- Fanconi anemia; complementation group D2
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human FANCD2 around the non-phosphorylation site of S222. Location: 160-240aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 166 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php