FANCD2 Antibody
Produktgrößen
100ul
£359,00
OASG02660-100UL
Über dieses Produkt
- SKU:
- OASG02660
- Zusätzliche Namen:
- FA4; FAD; FACD; FAD2; FA-D2; FANCD
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The Fanconi anemia complementation group (FANC) currently includes FANCA; FANCB; FANCC; FANCD1 (also called BRCA2); FANCD2; FANCE; FANCF; FANCG; FANCI; FANCJ (also called BRIP1); FANCL; FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability; hypersensitivity to DNA crosslinking agents; increased chromosomal breakage; and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage; resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in two transcript variants encoding different isoforms.
- Gendetails:
- Fanconi anemia; complementation group D2
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human FANCD2 around the phosphorylation site of S222. Location: 160-240aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 166 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php