FADD Antibody
Produktgrößen
100ul
£359,00
OASG02626-100UL
Über dieses Produkt
- SKU:
- OASG02626
- Zusätzliche Namen:
- GIG3; MORT1
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain; this protein can be recruited by TNFRSF6/Fas-receptor; tumor necrosis factor receptor; TNFRSF25; and TNFSF10/TRAIL-receptor; and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein; which allows it to recruit caspase-8; and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
- Gendetails:
- Fas (TNFRSF6)-associated via death domain
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human FADD around the phosphorylation site of S194. Location: 130-210aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 28 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php