F8 Antibody - C-terminal region
Produktgrößen
100ul
£359,00
OASG02618-100UL
Über dieses Produkt
- SKU:
- OASG02618
- Zusätzliche Namen:
- AHF; F8B; F8C; HEMA; FVIII; DXS1253E
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes coagulation factor VIII; which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which; in the presence of Ca+2 and phospholipids; converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein; isoform a; which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein; isoform b; which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A; a common recessive X-linked coagulation disorder.
- Gendetails:
- coagulation factor VIII; procoagulant component
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the C-terminal region of human Factor VIII. Location: 2130-2210aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 300 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php