F7 Antibody
Produktgrößen
100ul
£359,00
OASG02617-100UL
Über dieses Produkt
- SKU:
- OASG02617
- Zusätzliche Namen:
- SPCA
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form; and is converted to an active form by either factor IXa; factor Xa; factor XIIa; or thrombin by minor proteolysis. Upon activation of the factor VII; a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated; and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions; the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.
- Gendetails:
- coagulation factor VII (serum prothrombin conversion accelerator)
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human Factor VII LC. Location: 140-220aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 17 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php