ERBB4 Antibody
Produktgrößen
100ul
£359,00
OASG02558-100UL
Über dieses Produkt
- SKU:
- OASG02558
- Zusätzliche Namen:
- HER4; ALS19; p180erbB4
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains; a transmembrane domain; a tyrosine kinase domain; a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however; not all variants have been fully characterized.
- Gendetails:
- erb-b2 receptor tyrosine kinase 4
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human ErbB-4 around the phosphorylation site of Y1284. Location: 1220-1300aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 180 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php