ESR1 Antibody
Produktgrößen
100ul
£359,00
OASG02537-100UL
Über dieses Produkt
- SKU:
- OASG02537
- Zusätzliche Namen:
- ER; ESR; Era; ESRA; ESTRR; NR3A1
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes an estrogen receptor; a ligand-activated transcription factor composed of several domains important for hormone binding; DNA binding; and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function; but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer; endometrial cancer; and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants; but the full-length nature of many of these variants has not been determined.
- Gendetails:
- estrogen receptor 1
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human ER Alpha around the non-phosphorylation site of Y537. Location: 470-550aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 66 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php