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Antikörper

EPOR Antibody

Produktgrößen
100ul
£359,00
OASG02517-100UL
Über dieses Produkt
SKU:
OASG02517
Zusätzliche Namen:
EPO-R
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding; this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase; phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Gendetails:
erythropoietin receptor
Host:
Rabbit
Immunogen:
Synthesized peptide derived from human EpoR around the phosphorylation site of Y426. Location: 370-450aa.
Isotyp:
IgG
Molekulargewicht:
65 kDa
Aufreinigung:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20C. Avoid repeated freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody