DCTN2 Antibody - C-terminal region
Produktgrößen
100ul
£359,00
OASG02258-100UL
Über dieses Produkt
- SKU:
- OASG02258
- Zusätzliche Namen:
- RBP50; DCTN50; HEL-S-77; DYNAMITIN
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a 50-kD subunit of dynactin; a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions; including ER-to-Golgi transport; the centripetal movement of lysosomes and endosomes; spindle formation; chromosome movement; nuclear positioning; and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
- Gendetails:
- dynactin 2 (p50)
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the C-terminal region of human Dynactin 2. Location: 310-390aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 50 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php