CDK2AP1 Antibody - middle region
Produktgrößen
100ul
£359,00
OASG02208-100UL
Über dieses Produkt
- SKU:
- OASG02208
- Zusätzliche Namen:
- DOC1; ST19; DORC1; doc-1; p12DOC-1
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2; and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit; which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Gendetails:
- cyclin-dependent kinase 2 associated protein 1
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human DOC-1. Location: 30-110aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 20 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php