DNMT3B Antibody - N-terminal region
Produktgrößen
100ul
£359,00
OASG02207-100UL
Über dieses Produkt
- SKU:
- OASG02207
- Zusätzliche Namen:
- ICF; ICF1; M.HsaIIIB
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- CpG methylation is an epigenetic modification that is important for embryonic development; imprinting; and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation; rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.
- Gendetails:
- DNA (cytosine-5-)-methyltransferase 3 beta
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the N-terminal region of human Dnmt3b. Location: 1-80aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 96 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php