DMTN Antibody
Produktgrößen
100ul
£359,00
OASG02130-100UL
Über dieses Produkt
- SKU:
- OASG02130
- Zusätzliche Namen:
- DMT; EPB49
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes; by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-dependent manner. This protein contains a core domain in the N-terminus; and a headpiece domain in the C-terminus that binds F-actin. When purified from erythrocytes; this protein exists as a trimer composed of two 48 kDa polypeptides and a 52 kDa polypeptide. The different subunits arise from alternative splicing in the 3' coding region; where the headpiece domain is located. Disruption of this gene has been correlated with the autosomal dominant Marie Unna hereditary hypotrichosis disease; while loss of heterozygosity of this gene is thought to play a role in prostate cancer progression. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Gendetails:
- dematin actin binding protein
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human Dematin around the phosphorylation site of S403. Location: 330-410aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 55 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php