DDX3X Antibody
Produktgrößen
100ul
£359,00
OASG02115-100UL
Über dieses Produkt
- SKU:
- OASG02115
- Zusätzliche Namen:
- DBX; DDX3; HLP2; DDX14; CAP-Rf; MRX102; MRXSSB
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- The protein encoded by this gene is a member of the large DEAD-box protein family; that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif; and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity; and unlike most DEAD-box helicases; the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation; mRNP assembly; pre-mRNA splicing; and mRNA export. In the cytoplasm; this protein is thought to be involved in translation; cellular signaling; and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.
- Gendetails:
- DEAD (Asp-Glu-Ala-Asp) box helicase 3; X-linked
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human DDX3 around the non-phosphorylation site of T322. Location: 440-520aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 73 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php