DCC Antibody - middle region
Produktgrößen
100ul
£359,00
OASG02098-100UL
Über dieses Produkt
- SKU:
- OASG02098
- Zusätzliche Namen:
- CRC18; CRCR1; MRMV1; HGPPS2; IGDCC1; NTN1R1
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules; and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK; also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts; and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor; and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.
- Gendetails:
- DCC netrin 1 receptor
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the Internal region of human DCC. Location: 410-490aa.
- Isotyp:
- IgG
- Molekulargewicht:
- 158 kDa
- Aufreinigung:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php